DETOXIFICATION AND BIOTRANSFORMATION
Like any process involving construction and demolition, our bodies build and remove substances constantly. The removal process is called biotransformation or detoxification. The liver is the primary organ of biotransformation, which has two distinct processes: Phase 1 by way of the actions of the Cytochrome P450 system… and Phase 2, which involves the alteration of these intermediary products to water soluble substances. These are excreted by the kidneys and the other organs of elimination: the colon and sweat glands.
The circumstances of modern life have tremendous impact on our detoxification systems. For starters, there is the overload of toxic substances we acquire from the environment. Thousands of novel chemicals have been introduced into the environment with inadequate safety testing, forcing us to try to detoxify substances that our systems were not designed to process.
Adding even more stress to our already overburdened detox systems, our modern food supply does not provide the proper nutrients in sufficient quantities to support detoxification, while overwhelming our bodies with preservatives, genetically modified foods, and antibiotics. Other activities such as excessive exercise, inadequate sleep, and alcohol consumption add to the burden. Supporting biotransformation can alleviate symptoms such as fatigue, headaches, malaise, and depression.
The Toxin Solution by Joseph Pizzorno, ND